Here you will find links to research pertaining to Churg Strauss Syndrome, vasculitis, drug studies and other subjects related in some way to CSS. Compared to other diseases, there have not been many studies on Churg Strauss Syndrome, mostly because it is so rare. However, we are very fortunate that the disease has been studied by some of the top researchers in the field. Please note that many of the authors of these research articles have been supportive of the CSSA and some are serving on our Medical Advisory Board.

The US National Library of Medicine has a search service that allows anyone with internet access to look for medical articles free of charge. (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi). PubMed makes it easy to look up diseases, medicines, research authors or any combination of the above. Typing in the key words “Churg Strauss” yields 1178 items, for example. Key words “Churg Strauss Prednisone" yields 76 items.

Here is a partial listing of some of the research. It is important to note that much research results in preliminary findings that should not be confused with established fact. These links are from Entrez PubMed. This section of the website is a work in progress and we will continually be adding to the information contained here.

1) Am J Med. 2003 Sep;115(4):284-90.
Churg-Strauss syndrome: clinical presentation, antineutrophil cytoplasmic antibodies, and leukotriene receptor antagonists.
Keogh KA, Specks U.
(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12967693)

2) Curr Rheumatol Rep. 2000 Oct;2(5):430-8.
Do vasculitis categorization systems really matter?
Jennette JC, Falk RJ.
(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11123094)

3) Curr Opin Rheumatol. 1992 Feb;4(1):9-15.
Disease associations and pathogenic role of antineutrophil cytoplasmic autoantibodies in vasculitis.
Jennette JC, Falk RJ.
(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=1543669)

4) Clin Exp Rheumatol. 2003 Nov-Dec;21(6 Suppl 32):S69-77.
Update on the pathogenesis of Churg-Strauss syndrome.
Hellmich B, Ehlers S, Csernok E, Gross WL.
(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14740430)

5) Expert Opin Pharmacother. 2004 Jan;5(1):25-35.
Recent progress in the pharmacotherapy of Churg-Strauss syndrome.
Hellmich B, Gross WL.
(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14680433)

6) Dtsch Med Wochenschr. 2003 Jul 4;128(27):1475-8.
[Interferon-alpha treatment of the Churg-Strauss syndrome]
Reissig A, Forster M, Mock B, Schilder C, Kroegel C.
(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12840770)

7) Arthritis Rheum. 2003 Apr 15;49(2):151-5.
Prevalence of antineutrophil cytoplasmic antibodies in patients with various pulmonary diseases or multiorgan dysfunction.
Vassilopoulos D, Niles JL, Villa-Forte A, Arroliga AC, Sullivan EJ, Merkel PA, Hoffman GS.
(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12687504)

8) Clin Chest Med. 1998 Dec;19(4):759-76, ix.
Pulmonary vasculitis.
Sullivan EJ, Hoffman GS.
(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9917965)

9) Crit Care Clin. 2002 Oct;18(4):855-79.
Vasculitis: Wegener granulomatosis, Churg-Strauss syndrome, microscopic polyangiitis, polyarteritis nodosa, and Takayasu arteritis.
Frankel SK, Sullivan EJ, Brown KK.
(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12418444)

10) Arthritis Rheum. 2001 Feb;44(2):469-73.
Elevated interleukin-4 and interleukin-13 production by T cell lines from patients with Churg-Strauss syndrome.
Kiene M, Csernok E, Muller A, Metzler C, Trabandt A, Gross WL.
(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11229479)

11) Pharmacoepidemiol Drug Saf. 2003 Dec 8;13(10):661. [Epub ahead of print]
Identification of patients with Churg-Strauss syndrome (CSS) using automated data.
Harrold LR, Andrade SE, Eisner M, Buist AS, Go A, Vollmer WM, Chan KA, Frazier EA, Weller PF, Wechsler ME, Davis KJ, Platt R.
(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15386588)

12) 1: J Rheumatol. 2002 Feb;29(2):388-91.
Delayed relapse of Churg-Strauss syndrome manifesting as colon ulcers with mucosal granulomas: 3 cases.
Memain N, De BM, Guillevin L, Wechsler B, Meyer O.
(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11838861)

13) J Allergy Clin Immunol. 2002 Jan;109(1):S1-19.
Asthma therapies and Churg-Strauss syndrome.
Lilly CM, Churg A, Lazarovich M, Pauwels R, Hendeles L, Rosenwasser LJ, Ledford D, Wechsler ME.
(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11799357)

14) Drug Saf. 1999 Oct;21(4):241-51.
Leukotriene modifiers and Churg-Strauss syndrome: adverse effect or response to corticosteroid withdrawal?
Wechsler ME, Pauwels R, Drazen JM.
(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10514017)

15) Mod Pathol. 2001 Dec;14(12):1284-93.
Recent advances in the diagnosis of Churg-Strauss syndrome.
Churg A.
(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11743052)

16) : Lancet. 1998 Jul 4;352(9121):32-3.
Steroids and Churg-Strauss syndrome.
Churg A, Churg J.
(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9800746)

17) 1: Chest. 1995 Aug;108(2):320-3.
Formes frustes of Churg-Strauss syndrome.
Churg A, Brallas M, Cronin SR, Churg J.
(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=7634860)

18) Am J Med. 2004 Jul 1;117(1):39-50.
The antineutrophil cytoplasmic antibody-associated vasculitides.
Seo P, Stone JH.
(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15210387)

19) 1: Best Pract Res Clin Rheumatol. 2001 Jun;15(2):315-33.
New approaches to treatment in systemic vasculitis: biological
therapies.
Levine SM, Stone JH.
(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11469824)

20) Med Klin (Munich). 2004 Sep;99(9):518-22.
[New Aspects in ANCA-Associated Vasculitides]
Lamprecht P.
(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15372181)

21)Ann Rheum Dis. 2003 Dec;62(12):1221-3.
Intravenous immunoglobulins in peripheral neuropathy associated with vasculitis.
Levy Y, Uziel Y, Zandman GG, Amital H, Sherer Y, Langevitz P, Goldman B, Shoenfeld Y.
(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14644864)

22) Intern Med. 2003 Apr;42(4):313-7.
When should immunosuppressants be prescribed to treat systemic vasculitides?
Guillevin L, Pagnoux C.
(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12729318)

23) Curr Opin Nephrol Hypertens. 2003 May;12(3):267-72.
New insights into the immunopathogenesis and treatment of small vessel vasculitis of the kidney.
Langford CA, Balow JE.
(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12698064)

24) Semin Respir Infect. 2003 Mar;18(1):17-22.
Does infection play a role in the pathogenesis of pulmonary vasculitis?
Capizzi SA, Specks U.
(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12652450)

25) Immunobiology. 2002 Dec;206(5):496-501.
Treatment of refractory Churg-Strauss-Syndrome (CSS) by TNF-alpha blockade.
Arbach O, Gross WL, Gause A.
(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12607724)

Below are some eMedicine articles which many people find after doing a Google search with the disease name.

Churg-Strauss syndrome by Mehran Farid-Moayer, MD. artcilce updated on May 5, 2004.
http://www.emedicine.com/med/topic2926.htm

Churg -Strauss Disease by Robert S Rust, Jr MD article updated on November 18, 2003.
http://www.emedicine.com/neuro/topic501.htm